Mark A Little Selected Research

Systemic Vasculitis

1/2021	Risk Factors for Severe Outcomes in Patients With Systemic Vasculitis and COVID-19: A Binational, Registry-Based Cohort Study.
9/2020	2020 international consensus on ANCA testing beyond systemic vasculitis.
12/2016	Changes in urinary metabolomic profile during relapsing renal vasculitis.
4/2015	Getting the balance right: adverse events of therapy in anti-neutrophil cytoplasm antibody vasculitis.
6/2012	Elevated active secretory sphingomyelinase in antineutrophil cytoplasmic antibody-associated primary systemic vasculitis.
1/2012	Anti-proteinase 3 anti-neutrophil cytoplasm autoantibodies recapitulate systemic vasculitis in mice with a humanized immune system.
10/2009	Renal transplantation in systemic vasculitis: when is it safe?
4/2009	Experimental autoimmune vasculitis: an animal model of anti-neutrophil cytoplasmic autoantibody-associated systemic vasculitis.
1/2006	Therapeutic effect of anti-TNF-alpha antibodies in an experimental model of anti-neutrophil cytoplasm antibody-associated systemic vasculitis.

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Mark A Little Research Topics

Disease

33	Vasculitis (Vasculitides) 11/2021 - 11/2004
22	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 01/2022 - 01/2012
13	Glomerulonephritis 01/2021 - 09/2004
9	Inflammation (Inflammations) 01/2021 - 05/2007
9	Systemic Vasculitis 01/2021 - 01/2006
6	Proteinuria 11/2021 - 01/2016
4	Infections 01/2022 - 04/2015
4	COVID-19 01/2022 - 01/2021
4	Microscopic Polyangiitis 09/2020 - 07/2012
4	Granulomatosis with Polyangiitis (Wegener's Granulomatosis) 09/2020 - 01/2012
4	Hemorrhage 06/2020 - 09/2005
3	Nephrotic Syndrome (Syndrome, Nephrotic) 11/2021 - 01/2016
3	Churg-Strauss Syndrome (Allergic Angiitis) 06/2020 - 01/2017
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2022 - 01/2014
2	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 11/2019
2	Neoplasms (Cancer) 09/2020 - 04/2015
2	Hematuria 01/2020 - 04/2009
2	Thrombosis (Thrombus) 07/2018 - 01/2002
2	Chronic Renal Insufficiency 01/2018 - 02/2009
2	Renal Insufficiency (Renal Failure) 01/2014 - 02/2013
1	Rare Diseases (Rare Disease) 01/2022
1	Nephritis 09/2020
1	Connective Tissue Diseases (Connective Tissue Disease) 09/2020
1	Autoimmune Hepatitis 09/2020
1	Ulcerative Colitis 09/2020
1	Anti-Glomerular Basement Membrane Disease (Goodpasture's Syndrome) 09/2020
1	Crohn Disease (Crohn's Disease) 09/2020
1	Liver Diseases (Liver Disease) 09/2020
1	Idiopathic Interstitial Pneumonias 09/2020
1	Endocarditis 09/2020
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 09/2020
1	Asthma (Bronchial Asthma) 06/2020
1	Skin Manifestations 06/2020
1	Kidney Diseases (Kidney Disease) 06/2020
1	Purpura 06/2020
1	Polyneuropathies (Polyneuropathy) 06/2020
1	Bites and Stings (Sting) 01/2020
1	DNA Virus Infections 01/2020
1	Thromboembolism 07/2018
1	Atrophy 01/2018
1	Frailty 10/2017
1	Fibrosis (Cirrhosis) 01/2017
1	Rheumatic Diseases (Rheumatism) 01/2017
1	Hypertension (High Blood Pressure) 01/2016
1	Lupus Nephritis 01/2016

Drug/Important Bio-Agent (IBA)

41	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 01/2022 - 11/2004
10	AntibodiesIBA 01/2021 - 09/2004
9	Peroxidase (Myeloperoxidase)IBA 09/2020 - 09/2005
8	CreatinineIBA 11/2021 - 02/2009
5	GlucocorticoidsIBA 01/2022 - 04/2015
5	Biomarkers (Surrogate Marker)IBA 11/2021 - 01/2016
5	AutoantibodiesIBA 09/2020 - 02/2011
5	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2019 - 08/2005
4	Rituximab (Mabthera)FDA Link 01/2019 - 08/2014
4	AutoantigensIBA 01/2019 - 07/2012
3	Immunoglobulin G (IgG)IBA 11/2018 - 01/2006
3	Myeloblastin (Proteinase 3)IBA 07/2012 - 01/2012
2	Proteins (Proteins, Gene)FDA Link 11/2021 - 01/2016
2	Pharmaceutical PreparationsIBA 09/2020 - 04/2009
2	AntigensIBA 09/2020 - 06/2020
2	CytokinesIBA 01/2020 - 01/2006
2	Methotrexate (Mexate)FDA LinkGeneric 01/2017 - 08/2005
2	Azathioprine (Imuran)FDA LinkGeneric 04/2015 - 08/2005
1	Antiviral Agents (Antivirals)IBA 01/2022
1	Interferon Type IIBA 01/2021
1	NucleoproteinsIBA 01/2021
1	Oxygen (Dioxygen)IBA 01/2021
1	1- (4- chlorophenylhydrazono)- 1- (4- chlorophenylamino)- 3,3- dimethyl- 2- butanoneIBA 01/2020
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	Sphingosine-1-Phosphate ReceptorsIBA 01/2020
1	InterferonsIBA 01/2020
1	Fingolimod Hydrochloride (FTY720)FDA Link 01/2020
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2020
1	SEW2871IBA 01/2020
1	HLA-DQ Antigens (HLA-DQ)IBA 11/2019
1	C-Reactive ProteinIBA 01/2019
1	tinostamustineIBA 11/2018
1	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2018
1	Alkylating AgentsIBA 11/2018
1	Histone Deacetylase InhibitorsIBA 11/2018
1	RivaroxabanIBA 07/2018
1	Dabigatran FDA Link 07/2018
1	Factor Xa InhibitorsIBA 07/2018
1	apixabanIBA 07/2018
1	edoxabanIBA 07/2018
1	Cystatin CIBA 01/2018
1	Mycophenolic Acid (Cellcept)FDA LinkGeneric 01/2017
1	Interleukin-10 (Interleukin 10)IBA 01/2017
1	Edetic Acid (EDTA)FDA Link 01/2017
1	Ketoglutaric Acids (Ketoglutaric Acid)IBA 12/2016
1	Citric Acid (Citrate)FDA LinkGeneric 12/2016
1	trimethyloxamine (trimethylamine N-oxide)IBA 12/2016
1	Inositol (Myoinositol)IBA 12/2016
1	hydroxide ionIBA 01/2016

Therapy/Procedure

8	Therapeutics 01/2022 - 06/2010
3	Kidney Transplantation 04/2016 - 10/2009
2	Plasma Exchange 01/2022 - 08/2005
2	Remission Induction 01/2017 - 10/2009
2	Transplantation 04/2016 - 10/2009